LINKAGE BETWEEN BRAIN-SEROTONIN CONCENTRATION AND THE SEX-SPECIFIC PART OF THE Y-CHROMOSOME IN MICE

Authors
TORDJMAN S ROUBERTOUX PL CARLIER M MOUTIER R ANDERSON G LAUNAY M DEGRELLE H
Citation
S. Tordjman et al., LINKAGE BETWEEN BRAIN-SEROTONIN CONCENTRATION AND THE SEX-SPECIFIC PART OF THE Y-CHROMOSOME IN MICE, Neuroscience letters, 183(3), 1995, pp. 190-192
Citations number
20
Categorie Soggetti
Neurosciences
Journal title
Neuroscience letters → ACNP
ISSN journal
03043940
Volume
183
Issue
3
Year of publication
1995
Pages
190 - 192
Database
ISI
SICI code
0304-3940(1995)183:3<190:LBBCAT>2.0.ZU;2-L
Abstract
The implication of the sex-specific part of the Y-chromosome (Y-S-SP) on brain serotonin (5-HT) level was investigated using congenic strain s for this chromosomal region. The 5-HT level, which was higher in the NZB than in the CBA/H strain of mice, was depleted by the transfer of the Y-S-SP from NZB on CBA/H whereas the transfer of the Y-S-SP from CBA/H on NZB had no effect. The variations of 5-HT levels were not cor related with plasma testosterone concentration which is also dependent of the Y-S-SP.