1,2,3-DIAZAPHOSPHOLO[1,5-A]PYRIDINES

Authors
BANSAL RK PANDEY G GUPTA R KARAGHIOSOFF K SCHMIDPETER A
Citation
Rk. Bansal et al., 1,2,3-DIAZAPHOSPHOLO[1,5-A]PYRIDINES, Synthesis, (2), 1995, pp. 173-175
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthesis → ACNP
ISSN journal
00397881
Issue
2
Year of publication
1995
Pages
173 - 175
Database
ISI
SICI code
0039-7881(1995):2<173:1>2.0.ZU;2-3
Abstract
Cyclocondensation of 2-alkyl-1-aminopyridinium iodides 1a-c with phosp horus trichloride in the presence of triethylamine gives 1,2,3-diazaph ospholol[,5-a]pyridines 2a-c. 1-Unsubstituted products 2a,b undergo di chlorophosphinylation at the 1-position. Hydrolysis causes rupture of the N=P bond in 2c leading to opening of the five-membered ring. Dimet hyl sulphate methylates 2c at N-3.