CLEAR-CELL CARCINOMA OF THE LIVER WITH SPONTANEOUS REGRESSION OF METASTASES

The purpose of this report is to establish in some detail a case of sp ontaneous regression of metastases secondary to a clear cell hepatocel lular carcinoma. A review of the hepatocellular carcinomas from this d epartment has been previously reported, and this particular study focu ses on the two lesions that have the microscopic classification referr ed to above. One young female patient was 23 at the time of resection of the clear cell carcinoma of the liver plus diffuse intrahepatic met astases. She has been followed carefully over the years and has been s een as recently as June 1993. At that time, studies including ultrason ic and CT scan examinations of liver were carried out, all of which we re negative for any evidence of residual disease. The evidence present ed in this report would seem to establish conclusively that a spontane ous regression of the metastases from a clear cell carcinoma of the li ver had occurred without any medication and without any obvious altera tion in diet or state of health. (C) 1994 Wiley-Liss, Inc.