ANTIMICROBIAL ACTIVITY OF CRENATINE, AN ALKALOID SYNTHESIZED FROM INDOLE

Authors
AJAYEOBA EO ADENIYI BA OKOGUN JI
Citation
Eo. Ajayeoba et al., ANTIMICROBIAL ACTIVITY OF CRENATINE, AN ALKALOID SYNTHESIZED FROM INDOLE, PTR. Phytotherapy research, 9(1), 1995, pp. 69-71
Citations number
9
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
PTR. Phytotherapy research → ACNP
ISSN journal
0951418X
Volume
9
Issue
1
Year of publication
1995
Pages
69 - 71
Database
ISI
SICI code
0951-418X(1995)9:1<69:AAOCAA>2.0.ZU;2-3
Abstract
Synthesized crenatine, a B-carboline alkaloid previously isolated from Quassia undulata (Guill & Perr) D. Dietr (Simaroubaceae) is shown to possess antibacterial but no antifungal activity. The activity was tes ted in vitro against seven Gram-positive, ten Gram-negative bacteria a nd a yeast at a concentration of 1 mg/mL. The compound was found to be more effective against Gram-positive than Gram-negative bacteria.