SYNTHESIS OF 3-AMINO 9-PHENYL AZETIDINE

Citation
E. Bacque et al., SYNTHESIS OF 3-AMINO 9-PHENYL AZETIDINE, Synthetic communications, 25(6), 1995, pp. 803-812
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
00397911
Volume
25
Issue
6
Year of publication
1995
Pages
803 - 812
Database
ISI
SICI code
0039-7911(1995)25:6<803:SO39A>2.0.ZU;2-X
Abstract
We report a convenient preparation of 3-amino 3-phenyl azetidine from N-benzhydryl 3-azetidinone. Our strategy involves a modified Strecker reaction using dibenzylamine as an amino equivalent followed by the di splacement of the cyano group by phenyl magnesium bromide and a final catalytic hydrogenation.