Jh. Greinwald et al., PERITONSILLAR ABSCESS - AN UNLIKELY CAUSE OF NECROTIZING FASCIITIS, The Annals of otology, rhinology & laryngology, 104(2), 1995, pp. 133-137
Cervical necrotizing fasciitis is a devastating polymicrobial soft tis
sue infection characterized by gas formation and extensive necrosis of
subcutaneous fat and fascia with extension to skin and muscle. Involv
ement of the head and neck is rare and is typically dental in origin.
Despite broad-spectrum antibiotics, mortality rates for this disease r
emain high. We report a successfully treated case of necrotizing fasci
itis arising from a peritonsillar abscess. Review of the literature re
veals only 6 other cases, with 3 successful outcomes. Early diagnosis,
broad-spectrum antibiotics, and aggressive surgical debridement are t
he cornerstones of therapy. The pathophysiology is typically a mixed a
erobic and anaerobic infection. Supportive treatment options such as h
yperbaric oxygen therapy and high-calorie supplemental nutrition may b
e of benefit. A comprehensive literature review of craniocervical necr
otizing fasciitis is presented. Factors associated with poor outcomes
include diabetes mellitus, mediastinitis, cardiovascular disease, and
peritonsillar abscess.