Study objective: To determine whether emergency patients with acute ch
est pain and low suspicion of acute myocardial infarction (AMI) can be
managed cost-effectively and safely in a dedicated chest pain center
(CPC) that incorporates mandatory stress testing. Methods: We assemble
d a prospective observational case series of consecutive adult patient
s transferred from the emergency department to a nine-bed, 23-hour CPC
in a 564-bed community hospital from January 13 through May 31, 1994.
In our institution, all emergency patients with acute nontraumatic ch
est pain of unclear origin, suggestive of myocardial ischemia but with
a low probability of AMI, are transferred to the CPC for further eval
uation. All patients in whom AMI is ruled out undergo individually app
ropriate cardiac diagnostic testing in accordance with CPC clinical gu
idelines. Patients with end-stage coronary artery disease transferred
to the CPC for a ''rule-out'' protocol only did not undergo further di
agnostic testing. Admitted and discharged patients were followed throu
gh chart review and telephone survey, respectively. Results: Of the 50
2 patients transferred to the CPC, 477 (95%) completed follow-up at 14
days. Four hundred ten (86%) were discharged home. Those discharged a
fter diagnostic evaluation yielded negative findings had 100% survival
and zero diagnosis of AMI at 5-month follow-up. Overall mortality and
incidence of AMI on long-term follow-up for all patients transferred
to the CPC were .4% and .2%, respectively. Sixty-seven patients (13%)
were admitted from the CPC, of whom 44 (66%) had a final diagnosis of
ischemic heart disease (IHD) or AMI. Twenty-four patients with IHD (55
%; 6% of stress-tested group) were identified only on further stress t
esting. Of these patients, seven underwent percutaneous transluminal c
oronary angioplasty or coronary artery bypass grafting during hospital
ization. All were discharged home without major morbidity. Four hundre
d twenty-four patients (84%) underwent stress testing. The cost of man
datory stress testing to identify one patient with IHD after AMI was r
uled out was $3,125. An average cost-per-case savings of 62% was achie
ved for each patient transferred to the CPC who would have been hospit
alized before the inception of the CPC. Conclusion: Mandatory stress t
esting is a safe, cost-effective, and valuable diagnostic and prognost
ic tool in CPC patients.