Rj. Zalenski et al., FEASIBILITY OF A RAPID DIAGNOSTIC PROTOCOL FOR AN EMERGENCY DEPARTMENT CHEST PAIN UNIT, Annals of emergency medicine, 29(1), 1997, pp. 99-108
Study objective: To evaluate the applicability of a short-stay protoco
l for exclusion of acute ischemic heart disease without hospital admis
sion and to analyze these results in the context of a conceptual model
. Methods: An observational study of patients who presented with chest
pain to the emergency department of an 886-bed inner-city municipal h
ospital and who needed hospital admission to rule out acute myocardial
infarction (AMI). Patients were assessed by ED attending physicians t
o determine eligibility for an alternative, 12-hour protocol in an ED
chest pain observation unit (CPOU) followed by immediate exercise test
ing. Outcome measures were proportion of patients eligible for the sho
rt-stay protocol, risk factor profile, and reasons for exclusion. Resu
lts: Of 500 patients screened, 446 had sufficient data points to deter
mine protocol eligibility. Of these, 238 (53.3%; 95% confidence interv
al [CI], 48.7% to 57.9%) were found to have low probability for AMI. A
fter study exclusion criteria were applied to the patient cohort, 63 p
atients (14.1%; 95% CI, 10.9% to 17.3%) were eligible for the protocol
. The most common reasons for exclusion were history of coronary arter
y disease (46%) and inability to perform an interpretable exercise tol
erance test (42%). Conclusion: Although most admitted patients with ch
est pain (53%) were at low probability for AMI, only a minority (14%)
were eligible for a short-stay protocol that required patients to be f
ree of known coronary artery disease and able to perform an exercise t
olerance test. Factors affecting the operations and efficiency of a CP
OU include clinical characteristics of the target patient population,
protocol tests used, and hospital occupancy and reimbursement patterns
.