Vertebral osteomyelitis is an unusual complication of pneumococcal inf
ection. This report describes a patient who presented with back pain a
nd lower extremity weakness after bacteremic pneumococcal pneumonia. M
agnetic resonance imaging showed destruction of the L-4-L-5 vertebral
bodies and thecal sac compression, and Streptococcus pneumoniae was is
olated from an aspirate of the disk space. We found only 10 other case
s of pneumococcal vertebral osteomyelitis in a review of the literatur
e. In these 11 cases the presentations were usually subacute, and the
onset of back pain was insidious. Elevated erythrocyte sedimentation r
ates were commonly noted, Computed tomography and magnetic resonance i
maging were most helpful in delineating the extent of involvement in p
atients seen in the last decade. Successful treatment included surgery
alone in 2 cases that occurred before the antibiotic era, surgery plu
s 6 weeks of antibiotic therapy in 1, and antibiotics alone for 4 week
s to 7 months in 5. Two patients seen in the preantibiotic era died.