CHONDROSARCOMA OF BONE - ONCOLOGIC AND FUNCTIONAL RESULTS

Citation
Cjm. Vanloon et al., CHONDROSARCOMA OF BONE - ONCOLOGIC AND FUNCTIONAL RESULTS, Journal of surgical oncology, 57(4), 1994, pp. 214-221
Citations number
13
Categorie Soggetti
Surgery,Oncology
ISSN journal
00224790
Volume
57
Issue
4
Year of publication
1994
Pages
214 - 221
Database
ISI
SICI code
0022-4790(1994)57:4<214:COB-OA>2.0.ZU;2-3
Abstract
A retrospective review of 27 patients (21 males and 6 females) with ch ondrosarcoma of bone was performed to evaluate the oncologic and funct ional results. The average age of the patients was 48 years (range: 17 -76). The tumor sites were pelvis in 10 cases, distal femur in 2, prox imal tibia in 3, rib in 2, and other in 10. One patient with Oilier's disease had chondrosarcoma at two different sites simultaneously. Surg ical stages were I A in 8 cases, I B in 8, II A in 1, and II B in 10. Two patients had no surgical treatment. Amputation was performed in 5 cases and en bloc resection in 20. An uncontaminated radical or wide s urgical margin was achieved in 13 of 25 cases. Additional surgery was performed in seven cases; for deep infection in one case and for local recurrence or metastasis in six, Local recurrence developed in seven patients (26%). At follow-up, four patients had died of disease (15%), one patient had died of another cause, and two patients were alive wi th disease (7%). No evidence of disease was found in 20 patients (74%) . The oncologic results of limb salvage and amputation in chondrosarco ma of the limbs were good, although there was one failure of limb salv age, caused by infection. Due to surgical inaccessibility, results of the management of chondrosarcoma of the pelvis were poor. The average functional evaluation of 16 patients (average follow-up: 104 months) w as 75% (range: 30-100). The Musculoskeletal Tumor Society ratings were excellent in four cases, good in seven, fair in four, and poor in one . (C) 1994 Wiley-Liss, Inc.