MULTISYSTEMIC INFLAMMATORY DISEASE IN A BORZOI DOG

A six-week-old female borzoi puppy from a brother-sister mating develo ped a generalised illness characterised by anorexia, temporary intenti on tremor, episodic pyrexia, tachypnoea, conjunctivitis, otitis and ne ck pain. Haematological abnormalities included an inflammatory leukogr am and regenerative anaemia. Blood cultures remained sterile; clinical chemistry values were unremarkable. The puppy had recurrent seizures and was euthanased when 18 weeks old. Post mortem examination revealed a multisystemic inflammatory disease involving thyroids, lymph nodes, spleen, pancreas, bladder and lung, but no lesions to account for the neurological signs. The cause of this generalised disease was not rec ognised. The histological features are unusual and resemble those desc ribed in other dogs of this breed.