EFFECT OF ANTIHYPERTENSIVE THERAPY IN PREECLAMPSIA ON LEVELS OF SERUMINTERLEUKIN-4

We investigated the effects of antihypertensive therapy on serum level s of interleukin-4 using InterTest-4 ELISA in 25 preeclamptic women; 1 4 were placed on treatment, while Ii were not. Comparison was made wit h 24 nonpreeclamptic pregnant controls, Interleukin-4 levels were sign ificantly lower in the controls than in the treated preeclamptic women (p < 0.001): 65.6 +/- 10.9 versus 106.1 +/- 13.2, 63.7 +/- 9.6 versus 119.8 +/- 11.4, 90.2 +/- 9.1 versus 123.3 +/- 15.7, and 65.6 +/- 3.6 versus 109.7 +/- 11.4 pg/ml, during antepartum, early intrapartum, lat e intrapartum-and postpartum periods, respectively, No significant dif ferences were detected between the therapy and no therapy subgroups (p > 0.05). This shows that antihypertensive therapy has no effect on in terleukin-4 levels.