In many radiotherapy facilities radiotherapy portal verification is cu
rrently a subjective process based on the visual comparison of a treat
ment or portal image with a prescription or simulation image. The reli
ability of this process is unknown. We describe here a study in which
16 observers (oncologists, physicists and therapists) independently ev
aluated the geometric accuracy of 530 treatment fields on 45 patients.
The treatment images were acquired by the BEAMVIEW(TM) on-line portal
imaging system (Siemens Medical Laboratories, Concord, CA, USA). Illu
strative examples of the large variation in observers' assessments of
the same field are given. The kappa statistic is used to evaluate the
degree of agreement between observers and between on-line (at the trea
tment unit) and off-line (in a quiet viewing room) assessments. The be
st interobserver agreement was between the four oncologists contributi
ng to the study although this level of agreement was rated only as ''f
air''. Comparison of on-line and off-line decisions made by therapists
exhibited ''poor'' agreement. This study has provided statistical con
firmation of the suspicions of many workers in the field of radiothera
py portal verification, viz that the subjective evaluation of field ac
curacy is unreliable. However, the degree of unreliability is surprisi
ngly large. The inconsistencies between observers documented in this s
tudy need to be clearly acknowledged in the development of protocols f
or the clinical use of on-line portal imaging systems. Acceptable reli
ability in radiotherapy portal verification will only be achieved when
subjective decision making is eliminated.