In recent years, several studies have been carried out concerning the
effect of psychosocial factors on the course of infection due to the h
uman immunodeficiency virus (HIV). After summarizing the current statu
s of general knowledge in the field of psychoimmunology, this article
reviews the results of studies conducted in regard to HIV. Two conclus
ions are reached. The first is that current research has not shown psy
chosocial factors to have any impact on either the immunity status of
seropositive patients or the medical complications inherent to AIDS. T
he second conclusion is that several types of intervention, in particu
lar psychoeducational approaches, stress management programs, and the
strengthening of social and family support, give good results where th
e psychosocial well-being of patients is concerned and should motivate
various health professionals to improve the focus of their interventi
ons. Furthermore, significant methodological weaknesses in several ind
exed studies are noted, and these should be rectified to enable future
studies to confirm or correct the present observations.