THE ASSOCIATION OF AGE AND SEXUAL HISTORY WITH THE SEVERITY OF THE HISTOLOGICAL-FINDINGS IN WOMEN WITH CERVICAL INTRAEPITHELIAL NEOPLASIA

We examined the demographic and behavioral data of 203 patients with h istological diagnosis of cervical intraepithelial neoplasia (CIN) to a ssess putative predictors of the most severe alterations (CIN grade II I). The variables significantly associated with the histological diagn osis of CIN III were time since first intercourse (odds ratio 5.33, 95 % CI 1.50-16.15), time since menarche (odds ratio 4.62; 95% CI 1.39-16 .05) and age (odds ratio 2.48, 95% CI 1.32-4.67). After multivariate a nalysis, the only independent variable still associated with CIN III w as the time since first intercourse (odds ratio 6.11, p < 0.05), It is concluded that, in patients with recently diagnosed GIN, the time sin ce first intercourse - rather than age, age at first intercourse or li fetime number of sex partners - is the information best associated wit h the severity of the disease.