A. Vincent et al., THE ROLE OF THE BASAL GANGLIA IN OBSESSIV E-COMPULSIVE DISORDERS - ANOVERVIEW, Canadian journal of psychiatry, 39(9), 1994, pp. 545-550
This article reviews the main clinical indicators linking the basal nu
clei to obsessive compulsive disorder (OCD). Various pathologies assoc
iated with lesions of the basal nuclei are examined, followed by a rev
iew of neuropharmacological, brain imaging and psychosurgical studies.
Once the role of the neostriatum in ritualistic behaviours has been c
larified, the symptoms of OCD are interpreted based on the hypothesis
of a lesion of the striato-orbito-frontal loop.