EVALUATION OF TABLETED MICROSPHERES OF DIPYRIDAMOLE

Authors
GURSOY A TURKOGLU M SENYUCEL B KALKAN K OKAR I
Citation
A. Gursoy et al., EVALUATION OF TABLETED MICROSPHERES OF DIPYRIDAMOLE, Drug development and industrial pharmacy, 21(4), 1995, pp. 503-507
Citations number
3
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
Drug development and industrial pharmacy → ACNP
ISSN journal
03639045
Volume
21
Issue
4
Year of publication
1995
Pages
503 - 507
Database
ISI
SICI code
0363-9045(1995)21:4<503:EOTMOD>2.0.ZU;2-F
Abstract
Microspheres of dipyridamole were prepared by solvent evaporation meth ods. The effect of additives Avicel PH 101, and beta cyclodextrin on t he release rate of tableted microspheres were studied. Incorporating A vicel or beta cyclodextrin increased the dipyridamole release rates in tableted microspheres. Beta cyclodextrin was found to be a good addit ive for microsphere tablets to increase the drug release rates without causing disintegration.