SYNTHESIS AND CHARACTERIZATION OF CYCLOMALTOHEPTAOSE-BASED METAL CHELANTS AS PROBES FOR INTESTINAL PERMEABILITY

Authors
CAPRETTA A MAHARAJH RB BELL RA
Citation
A. Capretta et al., SYNTHESIS AND CHARACTERIZATION OF CYCLOMALTOHEPTAOSE-BASED METAL CHELANTS AS PROBES FOR INTESTINAL PERMEABILITY, Carbohydrate research, 267(1), 1995, pp. 49-63
Citations number
30
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Carbohydrate research → ACNP
ISSN journal
00086215
Volume
267
Issue
1
Year of publication
1995
Pages
49 - 63
Database
ISI
SICI code
0008-6215(1995)267:1<49:SACOCM>2.0.ZU;2-D
Abstract
The syntheses of two cyclomaltoheptaose-based metal chelants, cyclomal toheptaose-ethylenediaminetetraacetate (CD-EDTA) and cyclomaltoheptaos e-diamide-disulfur (CD-DADS), are described. The chelant moieties are attached to the 6-position of a single pyranose in the cyclomaltohepta ose via a short diamine spacer chain. Characterization of these novel chelants has been achieved using NMR and MS techniques. The peculiar f luxional properties of the CD-EDTA molecules is also discussed.