INABILITY TO PERFORM BICYCLE ERGOMETRY PREDICTS INCREASED MORBIDITY AND MORTALITY AFTER LUNG RESECTION

The ability to successfully exercise has been used to assess the cardi opulmonary risk of thoracotomy for lung cancer. Because of musculoskel etal, neurologic, peripheral vascular, or behavioral problems, not all patients presenting for pulmonary resection are capable of exercising , Using a multifactorial cardiopulmonary risk index (CPRI) consisting of a cardiac risk index (CRI) and a pulmonary risk index, we studied 7 4 patients (60 capable of exercising and 14 incapable of exercising) w ho underwent thoracotomy for lung cancer resection. The groups were si milar in reference to history of pulmonary disease, preoperative pulmo nary function, and pulmonary risk index score. The no-exercise patient s were more likely to have a history of cardiac disease (64 vs 28%; p < 0.01) and had a higher CRI score (2.0 +/- 0.2 vs 1.4 +/- 0.1; p < 0. 05). Cardiopulmonary postoperative complications (POCs) and mortality were more likely among those in the no-exercise group vs those in the exercise group (POCs, 79 vs 35%, p < 0.01; mortality, 21 vs 2%, p < 0. 05). Among the eight no-exercise patients with a CPRI of 4 or more, al l eight suffered a POC (100%) and three died (38%). Using multiple log istic regression analysis, both the CPRI score and the inability to ex ercise were independently associated with increased risk for POCs. We conclude that patients unable to perform even minimal preoperative exe rcise are at substantially increased risk for morbidity and mortality after lung resection. This results both from greater identifiable preo perative cardiopulmonary risk factors (as assessed by the CPRI) and fr om an independent effect related to the inability to exercise.