Study objective: To contrast the effectiveness of 2- vs 6-month reeval
uation intervals on both clinical outcome and cost in patients requiri
ng continuous home oxygen therapy (HOT). Design: Prospective, randomiz
ed clinical trial. Setting: The outpatient program of a university-aff
iliated Veterans Affairs Medical Center (VAMC) Pulmonary Service. Pati
ents: Fifty patients were chosen from among a cohort of 200 patients c
urrently enrolled in our HOT program. All met specific arterial blood
gas criteria, were able to give informed consent, had at least 6 month
s of prior HOT usage, and did not have any illness expected to indepen
dently shorten life expectancy. Interventions: Baseline resting oxygen
now rates were prescribed based on the results of arterial blood gas
measurements so as to attain a PaO2 > 60 mm Hg. Flow rates were adjust
ed as needed during a 12-min walk to maintain pulse oximetry readings
> 90%. No adjustments in baseline flow rates were made during sleep, I
dentical evaluations were repeated at either 2- or B-month intervals.
Measurements and results: At 1-year follow-up, there were no significa
nt differences between the 2- and B-month groups in any of the clinica
l outcome parameters measured, ie, number of emergency department visi
ts, number of hospitalizations, number of days hospitalized, or mortal
ity. Total costs were not significantly different between the two grou
ps. Evaluation costs were less in the 6-month follow-up group. Conclus
ions: After attaining stability following at least 6 months of continu
ous HOT usage, patients receiving continuous HOT need not be routinely
reevaluated more frequently than every 6 months.