We present a ''topological'' formulation of arbitrarily shaped vortex
strings in four dimensional field theory. By using a large Higgs mass
expansion, we then evaluate the effective action of the closed Abrikos
ov-Nielsen-Olesen vortex string. It is shown that the effective action
contains the Nambu-Goto term and an extrinsic curvature squared term
with negative sign. We next evaluate the topological F-mu nu($) over t
ilde F-mu nu term in the case where the vortex string manifold extends
out to the boundary of the time direction of space-time and find that
it becomes the sum of an ordinary self-intersection number and Polyak
ov's self-intersection number of the world sheet swept by the vortex s
tring. These self-intersection numbers are related to the self-linking
number and the total twist number, respectively. Furthermore, the F-m
u nu($) over tilde F-mu nu term turns out to be the difference between
the sum of the writhing numbers and the linking numbers of the vortex
strings at the initial time and the one at the final time. When the v
ortex string is coupled to fermions, the chiral fermion number of the
vortex string becomes the writhing number (module Z) through the chira
l anomaly. Our formulation is also applied to ''global'' vortex string
s in a model with a broken global U(1) symmetry.