A. Troilius et B. Ljunggren, REFLECTANCE SPECTROPHOTOMETRY IN THE OBJECTIVE ASSESSMENT OF DYE LASER-TREATED PORT-WINE STAINS, British journal of dermatology, 132(2), 1995, pp. 245-250
At present, the treatment of choice for congenital capillary malformat
ions of the port-wine stain type (PWS) is the flashlamp pulsed dye las
er. Good results can be obtained in the majority of patients with this
technique, but there is a group of poor responders. In the search for
predictive tools to determine the therapeutic outcome, we have used a
new photoelectric reflectance instrument. Sixty-six patients with PWS
, mainly on the face, were treated with a pulsed dye laser during a 21
-month period. Using a hand-held reflectance photometer, erythema indi
ces were obtained for the PWS and normal skin. Based on these indices,
a relative blanching effect could be calculated. The therapeutic resu
lt was judged to be excellent in 19, good in 20, fair in 14 and poor i
n 13 patients. There was a good correlation (r=0.844) between the degr
ee of blanching and the therapeutic result. In the 'excellent' categor
y, an average blanching effect of 47% was present after the first trea
tment, and this increased to between 75 and 100% after successive trea
tments. In the 'poor' category, the blanching effect after one treatme
nt averaged 14%, increasing to only 40% after up to six treatments. It
thus seems to be possible to predict the outcome of therapy, which is
of considerable help in treatment planning. Reflectance measurements,
an objective estimate of blanching, correlate well with the clinical
results, and are helpful in monitoring and predicting the therapeutic
outcome in dye laser-treated PWS.