CALCINOSIS CUTIS FOLLOWING LIVER-TRANSPLANTATION - A COMPLICATION OF INTRAVENOUS CALCIUM ADMINISTRATION

Calcinosis cutis may be a complication of administration of intravenou s calcium solutions. We report four patients who developed calcinosis cutis following orthotopic liver transplantation, all of whom had rece ived calcium chloride solutions intravenously during surgery. There wa s no evidence of extravasation of the solutions. A gradual improvement of the lesions was seen in the subsequent months. This complication o f intravenous calcium infusions is probably related to the large amoun ts of blood-derived products and of calcium salts administered during surgery.