GENETIC DIVERSITY OF 3 DNA-FINGERPRINTING MARKERS IN A MEXICAN POPULATION

Each individual may be identified by characterizing its genetic materi al by DNA fingerprinting technology. its application in Mexico demands a knowledge of the allelic and genotypic diversity of the DNA markers and the probability that two individuals may have the same fingerprin t. in the present study the allelic and genotypic diversities of the l oci D12S11 (MS43A), D7S22 (g3) and D1S7 (MSI) were determined in 100 M exican students of the military school of medicine (Escuela Medico Mil itar de Mexico). The mean allelic frequency of the loci MS43A, g3, and MS1 was 0.01, 0.008 and 0.006, respectively. The heterozygosity of MS 43A and g3 was 98 and 99% for MS1. The probability that two individual s might have the same genetic pattern was 2.0 x 10(-4), 1.3 X 10(-4) a nd 7.2 x 10(-5) for the loci MS43A, g3 and MS1, respectively, and as l ow as 1.9 x 10(-12) for the three taken together, These data indicate that the genetic diversity of these DNA fingerprinting markers in the Mexican population is high enough to warrant its use in paternity test ing and in the identification of individuals in forensic medicine.