S. Goni et al., OXYTOCIN INDUCTION OF LABOR - A COMPARISON OF 20-MIN AND 60-MIN DOSE INCREMENT LEVELS, International journal of gynaecology and obstetrics, 48(1), 1995, pp. 31-36
Objectives: To compare the efficacy and complications of oxytocin dose
increments at 20- and 60-min intervals for induction of labor in wome
n with low parity. Methods: One hundred women of low parity requiring
induction of labor were randomly allocated to 20- and 60-min oxytocin
dose increments, 50 patients in each group. The basal oxytocin dose wa
s 1 milliunit/min and doubling of the oxytocin dose was done at interv
als of 20 and 60 min. Results: The group with 60-min increments had a
decreased incidence of uterine hyperstimulation, cesarean section and
operative vaginal delivery. The induction-delivery interval was simila
r in both groups. Conclusion: The oxytocin infusion regimen with incre
ments at 60-min intervals is safer than and equally effective as 20-mi
n incremental intervals.