Material damage through displacements per atom (DPA) and helium gas pr
oduction, as well as the tritium breeding and energy absorption in an
IFE (Inertial Fusion Energy) reactor chamber have been investigated wi
th variable coolant zone thickness using different liquids. Examples a
re given for HYLIFE-II (an IFE reactor design) energy conversion chamb
ers using Flibe (Li2BeF4), natural lithium and Li17Pb83 eutectic as bo
th coolant and wall protection. To achieve a useful energy density for
energy conversion purposes with sufficient tritium breeding (TBR = 1.
1), material protection (DPA < 100 and He < 500 appm in 30 years of op
eration) and shallow burial criteria, coolant zone thickness values ar
e found to be 56 cm for Flibe, 160 cm for natural lithium and 170 cm f
or Li17Pb83 with SS-304 as structural material. Material damage invest
igations are extended to structural materials made of SiC and graphite
for the same blanket. DPA values and He production rates in graphite
turn out to be comparable to those in SS-304. However, they are higher
in SiC, as compared to SS-304 and graphite.