Over a three-year period, 90 burn patients having split thickness skin
grafting were studied. The deep burn surface area ranged from 5 to 35
% of TBSA. All had a positive bacterial contamination of the burned ar
ea greater than > 100,000 organism per gram. The conventional method o
f burn management was used. All cases had preoperative baths and povid
one iodine soaks. Postoperative topical antibiotics were applied to th
e grafted site, selected by culture and sensitivity testing. There was
an 80-95% take of the graft in 87 cases, 50% in two cases, and in one
case there was complete graft loss. The latter was due to the presenc
e of another species of contamination not specified by the culture and
sensitivity at the time of surgery. Another five patients with a simi
larly infected recipient surface were grafted without applying the abo
ve protocol; this was considered as a ''control group''. Two out of fi
ve cases showed a graft take of less than <20% and there was complete
graft loss in the other three cases. This postulated that diligent cle
ansing with antiseptic soaks is effective in reducing the bacterial co
unt. Specific topical antibiotics inhibit the bacterial action on the
granulation tissue surface, as they do in vitro until early vasculariz
ation required for graft adhesion occurs. Using this simple protocol,
good graft take could be achieved even in the presence of bacterial co
ntamination; thus resulted in a shorter hospital stay.