REFRACTORY RHEUMATOID-ARTHRITIS - THERAPEUTIC OPTIONS

Authors
CASH JM WILDER RL
Citation
Jm. Cash et Rl. Wilder, REFRACTORY RHEUMATOID-ARTHRITIS - THERAPEUTIC OPTIONS, Rheumatic diseases clinics of North America, 21(1), 1995, pp. 1-18
Citations number
118
Categorie Soggetti
Rheumatology
Journal title
Rheumatic diseases clinics of North America → ACNP
ISSN journal
0889857X
Volume
21
Issue
1
Year of publication
1995
Pages
1 - 18
Database
ISI
SICI code
0889-857X(1995)21:1<1:RR-TO>2.0.ZU;2-0
Abstract
Because rheumatoid arthritis rarely remits, refractory disease is comm on. Attention should be paid to aggravating comorbid conditions. Pharm acologic options currently available include cyclosporin, high-dose me thotrexate, combination second-line agents, and creative use of cortic osteroids. The available literature is reviewed in this article and th e potential risks and benefits of the various options are discussed.