SULFADIAZINE-INDUCED SIALADENITIS

OBJECTIVE: To present a case of sialadenitis induced by sulfadiazine. CASE SUMMARY: A 50-year-old man with bronchitis developed swelling of the parotid glands and floor of the mouth as well as plugging in his e ars 2 hours after ingestion of Bronco-aseptilex (sulfadiazine, cyclama te, and guaiacol). Skin-prick tests performed with serial dilutions of sulfadiazine and Bronco-aseptilex were all negative. We then performe d oral challenge tests with Bronco-aseptilex, sulfadiazine, and other compounds of the commercial syrup. Enlargement of the salivary glands was observed after oral challenge tests with Bronco-aseptilex and sulf adiazine. CONCLUSIONS: We describe a patient who developed drug-induce d sialadenitis. The oral challenge test confirmed that sulfadiazine wa s the etiologic agent.