FREQUENCY OF ANTINUCLEAR ANTIBODIES IN MULTIPLE-SCLEROSIS

Authors
BARNED S GOODMAN AD MATTSON DH
Citation
S. Barned et al., FREQUENCY OF ANTINUCLEAR ANTIBODIES IN MULTIPLE-SCLEROSIS, Neurology, 45(2), 1995, pp. 384-385
Citations number
10
Categorie Soggetti
Clinical Neurology
Journal title
Neurology → ACNP
ISSN journal
00283878
Volume
45
Issue
2
Year of publication
1995
Pages
384 - 385
Database
ISI
SICI code
0028-3878(1995)45:2<384:FOAAIM>2.0.ZU;2-D
Abstract
We found anti-nuclear antibodies (ANA) in 26.7% of 150 relapsing-remit ting and in 30.4% of 23 chronic progressive definite multiple sclerosi s (MS) patients by retrospective chart review. These patients did not have systemic lupus erythematosus. Since ANA are not pathogenically re levant in MS, they are false-positive, and likely reflect systemic imm une dysregulation in MS.