D. Reiter et al., TUMEFACTIVE CARTILAGE PROLIFERATION AFTER RHINOPLASTY - A NEWLY REPORTED COMPLICATION, Archives of otolaryngology, head & neck surgery, 123(1), 1997, pp. 72-75
Objective: To describe and document the development of tumoral prolife
ration of cartilage in 4 patients after nasal surgery, a complication
that, to our knowledge, has not been reported before. Design: Similar
postoperative nasal masses were excised from 4 patients who underwent
rhinoplasty. Histopathologic evaluation was carried out to identify th
e nature of the lesions and to provide a basis for rational management
of similar lesions subsequently encountered. Setting: Academic tertia
ry referral center. Participants: Four healthy patients (3 women and 1
man) ranging in age from 21 to 49 years. Two of the patients underwen
t routine rhinoplasty with resection of cephalic margins of alar carti
lages, and 2 underwent augmentation procedures with implantation of au
ricular cartilage. Intervention: Discrete firm masses were excised fro
m each patient's nose approximately 1 year after the most recent rhino
plastic procedure was performed. Histological evaluation was carried o
ut on each specimen. Results: All 4 masses were found to consist of tu
mefactive proliferation of cartilage. Clonal proliferation and mild nu
clear atypia were observed. Conclusions: After rhinoplasty, progressiv
e asymmetrical fullness in or adjacent to cartilaginous structures or
graft material should suggest the possibility of tumefactive prolifera
tion of cartilage and should be evaluated with surgical exploration. A
ll areas of thickened cartilage should be excised completely, with imm
ediate auricular cartilage reconstruction of resulting anatomical defe
cts. Perichondrium should be completely removed from auricular cartila
ge implants in the nose, and mechanical injury to the graft should be
minimized. We strongly caution against morsellizing dorsal cartilage i
mplants for nasal reconstruction.