We have reviewed the relationships of food, nutrition and feeding prac
tices to various infections in the newborn. Tentative conclusions are
made: (a) the initial use of human milk (raw or pasteurized) continues
to offer advantages in the care of babies in intensive care; (b) atte
mpts to mimic the microbiological effects of breast milk by manipulati
on of the composition of infant formulas have o far achieved little su
ccess, but this is a rapidly developing field; (c) we are wary of the
widespread use of breast milk ''fortifiers'' until there is evidence t
hat they do not adversely affect the protective properties of breast m
ilk; (d) the doubtful advantages of nasojejunal feeding need to be wei
ghed against the increased bacterial contamination of the upper small
bowel; (e) systems monitoring in milk kitchens and the handling of fee
ds in the neonatal unit are an integral part of comprehensive neonatal
care; (f) to limit nosocomial infection, particular attention to the
faecal-food-oral route is necessary since there is potential for multi
plication of initial contamination of food.