A case of mesothelium-lined cyst of the adrenal gland is reported. Alt
hough more than 300 adrenal cysts have been reported in the literature
, epithelial cell-lined cysts are rare and comprise only 9% of the cas
es. An adrenal cyst was found, the lining cells of which had features
consistent with mesothelial cells. The inner surface of the cyst was l
ined by a single layer of cuboidal cells, which showed alcian blue pos
itive cellular outline. Immunohistochemically, the lining cells were p
ositively stained for keratin, epithelial membrane antigen and CA-125.
Electron microscopic examination revealed many long complex microvill
i and desmosomes in the lining cells. There was a basal lamina beneath
the cell layer. These morphological and immunohistochemical findings
indicated that the lining cell is derived from mesothelium.