GLUCOSE-TRANSPORT AND GLUCOSE-HOMEOSTASIS - NEW INSIGHTS FROM TRANSGENIC MICE

Authors
MUECKLER MM
Citation
Mm. Mueckler, GLUCOSE-TRANSPORT AND GLUCOSE-HOMEOSTASIS - NEW INSIGHTS FROM TRANSGENIC MICE, News in physiological sciences, 10, 1995, pp. 22-29
Citations number
15
Categorie Soggetti
Physiology
Journal title
News in physiological sciences → ACNP
ISSN journal
08861714
Volume
10
Year of publication
1995
Pages
22 - 29
Database
ISI
SICI code
0886-1714(1995)10:<22:GAG-NI>2.0.ZU;2-J
Abstract
Experiments with transgenic mice overexpressing glucose transporter is oforms demonstrate the preeminence of the transport step with respect to muscle glucose disposal and whole body glucose homeostasis. These s tudies suggest the feasibility of controlling diabetic hyperglycemia b y pharmacological or genetic enhancement of muscle glucose transport.