Despite the wide variety of rigid contact lens fitting philosophies fo
r the visual correction of keratoconus, questions remain, including wh
ich approach-flat, divided support, or steep-contributes the most towa
rd the preservation of a clear cornea, One goal of the Collaborative L
ongitudinal Evaluation of Keratoconus (CLEK) Pilot Study was to determ
ine the feasibility of managing early keratoconus patients with apical
clearance rigid contact lenses, Of 30 keratoconus patients identified
with at least 1 nonscarred cornea, 17 patients (30 eyes) were randoml
y assigned to a steep lens fitting protocol, After trial fitting with
a standardized lens design demonstrating minimum apical clearance, len
ses were dispensed whose base curve was 0.2 mm steeper than the minimu
m apical clearance lens, Patients were re-evaluated on a quarterly sch
edule concluding at 12 months, Changes in keratometry between baseline
and 12 months identified unequal steepening of the flat and steep cor
neal curvatures, suggestive of corneal molding, Best corrected rigid l
ens visual acuity measures illustrated no significant changes over the
course of the study. Clinically significant corneal compromise was tr
ansiently observed in some patients, Only 1 of 22 eyes completing the
pilot study and fitted with apical clearance developed mild corneal sc
arring.