Background. Radiation therapy plays an important role in the loco-regi
onal control of carcinoma of the cervix. Strict adherence to the radia
tion protocol, without the introduction of time breaks, has been shown
to favorably affect loco-regional control and survival, making adhere
nce a crucial variable for optimal outcome. Because carcinoma of the c
ervix is a common disease among Latinas, with survival rates worse tha
n those of other ethnic groups in this country, the pattern of adheren
ce to the prescribed radiation treatment among Latina patients seen at
Los Angeles County Hospital were studied. Methods. The records of 69
consecutive Latina patients with cervical cancer who received radiatio
n therapy at Los Angeles County Hospital were reviewed. Semistructured
interviews in a successive group of 30 similar patients were conducte
d to acquire preliminary information about their psychosocial characte
ristics. Results. The results demonstrate inferior rates of optimal ad
herence to radiation treatment among Latina immigrant patients when co
mpared with the rates reported in the literature for the general popul
ation of cervical cancer patients in United States (16 vs. 63%). Furth
ermore, a large subset of patients (20%) in the series elected to disc
ontinue treatment without a medical reason. When a comparable group of
Latina patients was interviewed, potential practical, psychologic, an
d cultural barriers to optimal care were identified. Conclusions. The
results from this exploratory study support the need for further studi
es to document the pattern of adherence to radiotherapy in the rest of
the country among this minority population. The results suggest that
an intervention to improve information and adherence to radiation ther
apy may be necessary to assure Latinas a chance for rates of cure comp
arable with the national standards.