Yf. Hung et al., NEW REACTION-MECHANISM FOR THE OSCILLATORY PEROXIDASE OXIDASE REACTION AND COMPARISON WITH EXPERIMENTS, Journal of physical chemistry, 99(7), 1995, pp. 1980-1987
We present a new model for the oscillatory peroxidase-oxidase reaction
, which is an extension of the recent model C (Aguda, B. D.; Larter, R
. J. Am. Chem. Soc. 1991, 113, 7913) and includes reaction steps invol
ving 2,4-dichlorophenol and termination reactions for the superoxide r
adical and hydrogen peroxide. The calculations with this model compare
well with measurements of temporal variations, including mixed-mode,
chaotic, and bursting oscillations as well as tests for the assignment
of roles of the species in the model and the categorization of the os
cillator (Eiswirth, M.; Freund, A.; Ross, J. Adv. Chem. Phys. 1991, 80
, 127). Of the 12 species considered in this model, six are essential,
and the others nonessential. The essential species are oxygen, compou
nd I, compound II, compound III, the NAD radical, and the superoxide r
adical. The nature of these essential species is also identified. Of t
he four species (oxygen, NADH, native HRP, and compound III) measured
experimentally, oxygen and compound UI have been determined to be esse
ntial. The category of this model is 1CW, in accordance with the exper
imental results. The new model reproduces better than the earlier mode
ls the temporal variations observed experimentally.