N. Woodford et al., LINKAGE OF VANCOMYCIN AND HIGH-LEVEL GENTAMICIN RESISTANCE GENES ON THE SAME PLASMID IN A CLINICAL ISOLATE OF ENTEROCOCCUS-FAECALIS, Journal of antimicrobial chemotherapy, 35(1), 1995, pp. 179-184
A transferable 55-MDa plasmid which encoded resistance to both vancomy
cin and high concentrations of gentamicin was identified in a clinical
isolate of Enterococcus faecalis. The plasmid hybridized with probes
for the vanB and aac6' aph2'' resistance genes. This is the first repo
rt of linkage of glycopeptide and high-level aminoglycoside resistance
genes in an Enterococcus sp.