ASYMMETRIC-SYNTHESIS .35. SYNTHESIS OF 2-METHYL 5-SUBSTITUTED PIPERIDINES FROM CHIRAL NON-RACEMIC LACTAMS

Authors
VAREA T DUFOUR M MICOUIN L RICHE C CHIARONI A QUIRION JC HUSSON HP
Citation
T. Varea et al., ASYMMETRIC-SYNTHESIS .35. SYNTHESIS OF 2-METHYL 5-SUBSTITUTED PIPERIDINES FROM CHIRAL NON-RACEMIC LACTAMS, Tetrahedron letters, 36(7), 1995, pp. 1035-1038
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
7
Year of publication
1995
Pages
1035 - 1038
Database
ISI
SICI code
0040-4039(1995)36:7<1035:A.SO25>2.0.ZU;2-C
Abstract
A series of 2-methyl-5-substituted piperidines in enantiomerically pur e form has been synthesized from lactam 3a. The stereospecific alkylat ion involved a rigid amide enolate.