U. Dalessandro et al., MORTALITY AND MORBIDITY FROM MALARIA IN GAMBIAN CHILDREN AFTER INTRODUCTION OF AN IMPREGNATED BEDNET PROGRAM, Lancet, 345(8948), 1995, pp. 479-483
After the success of a controlled trial of insecticide-treated bednets
in lowering child mortality, The Gambia initiated a National Insectic
ide Impregnated Bednet Programme (NlBP) in 1992 with the objective of
introducing this form of malaria control into all large villages in Th
e Gambia. Five areas (population 115 895) were chosen as sentinel site
s for evaluation of the NlBP. During the first year of intervention a
25% reduction was achieved in ail-cause mortality in children 1-9 year
s old living in treated villages (rate ratio 0.75 [95% CI 0.57-0.98],
p=0.04). If one area where the programme was ineffective was excluded,
the was 38% (0.62 [0.46-0.83), p=0.001). A in rates of parasitaemia a
nd high-density parasitaemia, an increase in mean packed-cell volume (
rate ratio 0.75 [95% Cl 0.59-0.98], p=0.04) and an improvement in the
nutritional status of children living in treated villages were also de
tected. In a country such as The Gambia, where nets were widely used a
nd which has a good primary health care system, it is possible to achi
eve insecticide-treatment of bednets at a national level with a signif
icant reduction in child mortality; but at a cost which the country ca
nnot afford.