MORTALITY AND MORBIDITY FROM MALARIA IN GAMBIAN CHILDREN AFTER INTRODUCTION OF AN IMPREGNATED BEDNET PROGRAM

Citation
U. Dalessandro et al., MORTALITY AND MORBIDITY FROM MALARIA IN GAMBIAN CHILDREN AFTER INTRODUCTION OF AN IMPREGNATED BEDNET PROGRAM, Lancet, 345(8948), 1995, pp. 479-483
Citations number
17
Categorie Soggetti
Medicine, General & Internal
Journal title
LancetACNP
ISSN journal
01406736
Volume
345
Issue
8948
Year of publication
1995
Pages
479 - 483
Database
ISI
SICI code
0140-6736(1995)345:8948<479:MAMFMI>2.0.ZU;2-O
Abstract
After the success of a controlled trial of insecticide-treated bednets in lowering child mortality, The Gambia initiated a National Insectic ide Impregnated Bednet Programme (NlBP) in 1992 with the objective of introducing this form of malaria control into all large villages in Th e Gambia. Five areas (population 115 895) were chosen as sentinel site s for evaluation of the NlBP. During the first year of intervention a 25% reduction was achieved in ail-cause mortality in children 1-9 year s old living in treated villages (rate ratio 0.75 [95% CI 0.57-0.98], p=0.04). If one area where the programme was ineffective was excluded, the was 38% (0.62 [0.46-0.83), p=0.001). A in rates of parasitaemia a nd high-density parasitaemia, an increase in mean packed-cell volume ( rate ratio 0.75 [95% Cl 0.59-0.98], p=0.04) and an improvement in the nutritional status of children living in treated villages were also de tected. In a country such as The Gambia, where nets were widely used a nd which has a good primary health care system, it is possible to achi eve insecticide-treatment of bednets at a national level with a signif icant reduction in child mortality; but at a cost which the country ca nnot afford.