SYNTHESIS OF 2-(ALPHA-FLUOROBENZYL)BENZIMIDAZOLE DERIVATIVES

Authors
HIDA F BENEY C ROBERT J LUUDUC C
Citation
F. Hida et al., SYNTHESIS OF 2-(ALPHA-FLUOROBENZYL)BENZIMIDAZOLE DERIVATIVES, Journal of fluorine chemistry, 70(2), 1995, pp. 233-236
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear
Journal title
Journal of fluorine chemistry → ACNP
ISSN journal
00221139
Volume
70
Issue
2
Year of publication
1995
Pages
233 - 236
Database
ISI
SICI code
0022-1139(1995)70:2<233:SO2D>2.0.ZU;2-R
Abstract
New 2-(alpha-fluorobenzyl)benzimidazole derivatives have been prepared . Fluorination was carried out from benzylic alcohols using 2-chloro-1 ,1,2-trifluorotriethylamine reagent. The scope and the rates of format ion of the resulting products are dependent on the nature of the subst ituents. Physical data, H-1 and F-19 NMR chemical shifts of the hydrox y and fluorine compounds are given.