EFFECTS OF MILK AND FOOD ON THE ABSORPTION OF ENOXACIN

The effects of milk and a standard breakfast on the oral absorption of enoxacin were evaluated in eight healthy volunteers in a randomized, balanced, four-way crossover study. After an overnight fast, 400 mg en oxacin was given with water, milk, a breakfast or with a breakfast and milk. The extent of enoxacin absorption was not affected by any of th e three treatments, and no statistically significant changes were foun d with respect to peak plasma enoxacin concentration or time to peak. We conclude that enoxacin can be taken together with food and dairy pr oducts.