ASSOCIATION BETWEEN HAPLOTYPES, HIND III-VNTR ALLELES AND MUTATIONS AT THE PAH LOCUS IN SICILY

Authors
ROMANO V CALI F GULDBERG P GUTTLER F INDELICATO A BOSCO P CERATTO N
Citation
V. Romano et al., ASSOCIATION BETWEEN HAPLOTYPES, HIND III-VNTR ALLELES AND MUTATIONS AT THE PAH LOCUS IN SICILY, Acta paediatrica, 83, 1994, pp. 39-40
Citations number
7
Categorie Soggetti
Pediatrics
Journal title
Acta paediatrica → ACNP
ISSN journal
08035253
Volume
83
Year of publication
1994
Supplement
407
Pages
39 - 40
Database
ISI
SICI code
0803-5253(1994)83:<39:ABHHIA>2.0.ZU;2-1
Abstract
In this study we report previously undescribed associations between mu tations, haplotypes and a minisatellite polymorphism (Hind III VNTR) o f the PAH gene in the Sicilian population. Analysis of the association between mutations and linked polymorphisms between Sicilians and othe r Mediterranean populations may be a useful tool to study the time-spa ce origin of mutant PAH genes in Southern Europe.