K. Rockwood et al., SCREENING FOR COGNITIVE IMPAIRMENT IN THE ELDERLY - IMPACT OF PHYSICAL FUNCTION MEASURES ADDED TO COGNITIVE SCREENING INSTRUMENTS, Neuropsychology, development, and cognition. Section B, Aging and cognition, 1(4), 1994, pp. 261-270
This study examines the relationship between cognitive impairment and
impaired physical function to determine if the sensitivity and specifi
city of the Modified Mini-Mental State Examination (3MS) can be improv
ed by the addition of physical function measures. One hundred and sixt
y-two subjects from the Nova Scotia sample of the Canadian Study of He
alth and Aging were studied. Subjects were tested using the 3MS and ph
ysical function measures prior to undertaking a detailed clinical exam
ination. Receiver Operating Characteristic (ROC) curves were construct
ed to determine optimal cutpoints for the 3MS and a new 3MS score whic
h included physical function measures. While the 3MS distinguished dem
ented from unimpaired subjects (.9618), it showed less efficiency for
classification of unimpaired subjects and subjects who have cognitive
impairment without dementia (.7536). The addition of physical function
data increased performance of the 3MS in its ability to discriminate
unimpaired from demented subjects (.9854), but not significantly. The
relationship between cognitive impairment and functional impairment ne
eds clearer definition in cognitively impaired yet non-demented indivi
duals. The addition of widely used function measures is inadequate in
improving the parameters of the 3MS as a screening instrument.