We evaluated the efficacy of forced-air warming to maintain normotherm
ia during liver transplantation. In a prospective clinical trial 20 pa
tients were randomly assigned to routine thermal management (circulati
ng-water mattress set at 42 degrees C, intravenous fluid warming to 37
degrees C and passive insulation) or routine management with addition
al forced-air warming of head, chest, and arms. Core temperature was m
easured in the pulmonary artery. Morphometric and demographic characte
ristics were similar in each group, as was total administered fluid vo
lume replacement. Core temperatures in each group decreased by about 0
.6 degrees C during the first 70 min of anaesthesia and then by 0.9 de
grees C within 90 to 120 min in the patients given routine thermal man
agement, but only by 0.4 degrees C in those warmed with forced-air. Su
bsequently, core temperatures in the control group increased to only 3
5.7, SD 0.25 degrees C whereas those in the patients given forced-air
warming increased to 36.5, SD 0.2 degrees C. Despite the relatively hi
gh ambient temperature, patients warmed only with a circulating-water
mattress and passive insulation became hypothermic during surgery. In
contrast, when forced-air warming was added to this routine thermal ma
nagement, patients were normothermic at the end of surgery. Forced-air
warming prevented intra-operative hypothermia during liver transplant
ation.