NEUROENDOCRINE AND NEUROPHYSIOLOGIC CHANGES OF ADOLESCENCE

This paper reviews the changes of adolescence that affect neuroendocri ne and neurophysiologic functions. Normal variability in onset and pro gression of pubertal stages is discussed. The effects of hypothalamic and pituitary maturation and resulting changes in circulating hormone levels at the onset of secondary sexual characteristics are reviewed. Several theories and research data regarding the causes of the onset o f puberty are identified. Abnormal symptoms of pubertal development ar e reviewed, and suggestions made for the Cleft Palate-Craniofacial tea m to monitor these symptoms.