The prevalence of gastrointestinal diseases markedly differs between d
eveloped and developing countries because of the poor sanitation, hygi
ene, impure water and food ingestion, widespread illiteracy and povert
y in the developing world. The incidence of gastrointestinal diseases
such its diarrhoea, cholera, typhoid, dysentery, viral hepatitis (A an
d E virus) can be substantially reduced by providing clean water and f
ood to the population. Restricting consumption of tobacco and non-ster
oidal anti-inflammatory drugs will reduce diseases and/or complication
s of the upper gastrointestinal tract. Diminishing alcohol intake and
overuse of blood transfusion and improving blood banks would prevent m
any acute and chronic liver diseases. Costly passive and active immuno
prophylaxis wilt become unnecessary a these measures are undertaken.