New developments in 3-D volume acquisitions are creating a rapidly inc
reasing demand for integrating multimodality 3-D visualization. In ord
er to accomplish routine clinical multimodality visualization, many is
sues have to be dealt with, such as techniques for accurate spatial re
gistration, integrated representation, suitable graphical user interfa
ces, and obtaining adequate rendering speeds. The aim of this experien
ce paper is 2-fold. First, it presents various results from our resear
ch on multimodality visualization/registration. Second, this paper exp
licitly addresses practical problems and findings related to software
development and multimodality registration/visualization. We hope that
this will give colleagues a better understanding in some of these iss
ues based on our experience, including notably our mistakes. Copyright
(C) 1996 Elsevier Science Ltd.