THE FORMATION OF PROTEIN DISULFIDE BONDS

Authors
FREEDMAN RB
Citation
Rb. Freedman, THE FORMATION OF PROTEIN DISULFIDE BONDS, Current opinion in structural biology, 5(1), 1995, pp. 85-91
Citations number
53
Categorie Soggetti
Cell Biology",Biology
Journal title
Current opinion in structural biology → ACNP
ISSN journal
0959440X
Volume
5
Issue
1
Year of publication
1995
Pages
85 - 91
Database
ISI
SICI code
0959-440X(1995)5:1<85:TFOPDB>2.0.ZU;2-5
Abstract
The past year has provided more detail on the formation of native disu lphide bonds during protein folding at biosynthesis and has identified important cellular factors in the oxidative folding compartments, nam ely the eukaryotic endoplasmic reticulum and the bacterial periplasm. This information has enabled traditional in vitro refolding studies to be re-evaluated and their relevance as models for folding in the cell to be established.