COMPLEX TREATMENT OF LOCALLY SPREAD CARCI NOMA OF THE RECTUM

From analysis of 490 case records of patients with stage IV A rectal c arcinoma, 3 groups of patients were distinguished according to the siz e of the tumor and the degree of its fixation to the surrounding tissu es and growth into the adjacent organs. Such locally spread tumors of the rectum must be subjected to combined treatment: preoperative large -fractional radiotherapy in concurrent local SHF-hyperthermia followed by operation 24-48 hours later. If respectability of the tumor is dou btful, a relieving colostoma is formed in the first stage and distance gammatherapy is applied in a dose of 4 Gy twice a week to a total dos e of 32 Gy auring medication with metronidazole and local SHF-therapy. Concurrent intraarterial chemotherapy with 5-fluorouracil (15 mg/kg b ody weight) has been lately introduced into practice in the treatment of such patients. The results of this complex treatment are evaluated 3-4 weeks after the course is completed.